Vilitra 60mg Tablets: High-Dose Vardenafil Uses, Effects & Safety
Vilitra 60mg is a high-strength vardenafil tablet marketed for erectile dysfunction (ED) in adult men. Each tablet is marketed as containing 60mg of vardenafil, a PDE5 inhibitor related to sildenafil and tadalafil.
The strength needs careful context. 60mg is not a standard recommended vardenafil dose for erectile dysfunction. Licensed vardenafil treatment normally starts at 10mg before anticipated sexual activity. Depending on effectiveness and tolerability, the dose may be reduced to 5mg or increased to a maximum of 20mg.
Vilitra 60mg therefore contains three times the maximum standard vardenafil ED dose.
This does not mean it produces three times the erectile effect. Higher drug exposure can increase adverse effects, and moving beyond 20mg is not the established treatment pathway when standard vardenafil fails.
This guide explains what Vilitra 60mg is, how vardenafil works, how 60mg compares with standard 10mg and 20mg doses, what clinical research tells us about high-dose vardenafil, possible side effects, important heart and drug interactions, and the UK regulatory considerations surrounding high-strength ED medicines.
Vilitra 60mg at a Glance
| Active ingredient | Vardenafil |
|---|---|
| Stated strength | 60mg |
| Medicine class | PDE5 inhibitor |
| Marketed use | Erectile dysfunction in adult men |
| Usual licensed starting dose | 10mg |
| Maximum recommended vardenafil dose | 20mg |
| Is 60mg a standard ED dose? | No |
| Approximate standard timing | 25 to 60 minutes before sexual activity |
| Maximum recommended frequency | Once per day |
| Sexual stimulation required? | Yes |
What Is Vilitra 60mg?
Vilitra 60mg is a tablet marketed under the Vilitra brand and containing vardenafil.
Centurion Laboratories lists Vilitra among its vardenafil products, including high-strength versions such as Vilitra 40, Vilitra 60 and Vilitra 80.
Vardenafil itself is an established erectile dysfunction medicine. It belongs to the same broad PDE5-inhibitor family as:
- Sildenafil
- Tadalafil
- Avanafil
The unusual aspect of Vilitra 60 is therefore not the active ingredient. It is the dose.
Licensed vardenafil tablets are normally used at strengths of 5mg, 10mg or 20mg. Sixty milligrams falls well outside that standard treatment range.
What Is Vilitra 60mg Used For?
Vilitra 60mg is marketed for erectile dysfunction.
Erectile dysfunction means repeatedly having difficulty achieving or maintaining an erection that is firm enough for satisfactory sexual activity.
Occasional erection problems are extremely common and can happen because of stress, tiredness, alcohol or anxiety.
Persistent ED can sometimes be associated with:
- Cardiovascular disease
- High blood pressure
- High cholesterol
- Diabetes
- Obesity
- Smoking
- Nerve damage
- Low testosterone or another hormonal problem
- Depression or anxiety
- Performance anxiety
- Certain prescription medicines
Vardenafil can improve erectile function, but recurrent ED is worth assessing because treating the erection problem does not necessarily address the underlying cause.
How Does Vardenafil Work?
Vardenafil is a phosphodiesterase type 5 inhibitor, commonly shortened to PDE5 inhibitor.
During sexual stimulation, nitric oxide is released in erectile tissue. This increases levels of a chemical called cyclic guanosine monophosphate, or cGMP.
cGMP relaxes smooth muscle inside the penis and allows more blood to enter erectile tissue.
An enzyme called PDE5 breaks cGMP down.
Vardenafil temporarily inhibits PDE5, allowing the natural erection-related signal to remain active more effectively.
This can make it easier to achieve and maintain an erection when sexual stimulation occurs.
Vardenafil does not automatically create an erection. Sexual stimulation is still required.
Is Vilitra 60mg a High Dose?
Yes. 60mg is a very high vardenafil dose in the context of erectile dysfunction treatment.
Licensed vardenafil dosing normally follows this range:
- 5mg: lower dose where appropriate
- 10mg: usual recommended starting dose
- 20mg: maximum recommended dose
A Vilitra 60mg tablet therefore contains:
- Six times the usual 10mg starting dose
- Three times the maximum recommended 20mg dose
The number of milligrams does not translate directly into erection quality. Three times the drug does not mean three times the erection, three times the reliability or three times the duration.
It does mean substantially greater drug exposure.
Is Vardenafil 60mg an Approved ED Dose?
60mg is not part of the standard licensed vardenafil dosing regimen for erectile dysfunction in the UK.
The recommended starting dose for standard film-coated vardenafil tablets is 10mg taken when needed approximately 25 to 60 minutes before sexual activity.
Depending on effectiveness and side effects, the dose may be increased to 20mg or decreased to 5mg.
The maximum recommended dose is 20mg.
This means commercially available Vilitra 60mg should not be confused with an ordinary licensed vardenafil treatment strength simply because the active ingredient itself is medically established.
Vilitra 20mg vs Vilitra 60mg
This is the most important comparison for anyone researching Vilitra 60mg.
| Feature | Vardenafil 20mg | Vilitra 60mg |
|---|---|---|
| Vardenafil content | 20mg | 60mg |
| Within standard licensed ED range? | Yes | No |
| Maximum standard ED dose? | Yes | No |
| Relative dose | 1x | 3x |
| Standard next step if 20mg fails? | Not applicable | No |
If an appropriate 20mg vardenafil dose repeatedly fails, the standard response is not to triple the dose.
The cause of poor treatment response should be considered instead.
Vilitra 10mg vs Vilitra 60mg
Ten milligrams is the normal starting dose of licensed vardenafil for erectile dysfunction.
Vilitra 60mg contains six times that amount.
For someone who has never used vardenafil, jumping directly to a 60mg product bypasses the established dose range entirely.
The general medical principle is to find an effective dose with acceptable side effects rather than beginning with the largest tablet available.
Vilitra 40mg vs Vilitra 60mg
Both 40mg and 60mg exceed the usual licensed vardenafil dose range for ED.
Compared with the standard 20mg maximum:
- 40mg contains twice the maximum recommended dose.
- 60mg contains three times the maximum recommended dose.
The existence of commercial tablets at these strengths does not establish them as routine or approved erectile dysfunction doses.
Does Vardenafil 60mg Work Better Than 20mg?
There is no standard licensed treatment recommendation that says a man who does not respond to vardenafil 20mg should move to 40mg or 60mg.
Twenty milligrams is already the maximum recommended standard dose.
If 20mg repeatedly provides an inadequate response, possible reasons include:
- Insufficient sexual stimulation
- Severe vascular erectile dysfunction
- Diabetes-related blood-vessel or nerve damage
- Neurological disease
- Low testosterone
- Performance anxiety
- Heavy alcohol intake
- Another medicine contributing to ED
- Vardenafil simply not being the best PDE5 inhibitor for that individual
In those situations, investigating the reason treatment is failing may be considerably more useful than simply multiplying the dose.
Have High Doses of Vardenafil Been Studied?
Yes. Vardenafil doses above the standard treatment range have been examined during clinical development and safety studies.
Single doses up to 80mg have been administered to healthy volunteers in controlled studies.
That fact needs to be interpreted correctly.
High-dose safety studies are designed to understand what happens at increased exposure. They do not automatically establish those doses as appropriate treatments for erectile dysfunction.
Despite higher doses having been investigated, the recommended ED dose ceiling remains 20mg.
Vardenafil 60mg and Heart Rhythm: What About the QT Interval?
Vardenafil has an additional cardiac consideration that deserves more attention than it gets on many ED-product pages: the QT interval.
The QT interval is part of the heart’s electrical cycle and can be measured on an ECG.
Clinical studies have examined vardenafil at both normal and very high doses. Single doses of 10mg and 80mg produced measurable increases in the QTc interval.
The clinical importance of these changes is not fully clear, but licensed vardenafil guidance recommends particular caution in people with risk factors for QT prolongation.
This includes people with:
- Congenital long QT syndrome
- Low potassium levels
- Certain heart-rhythm conditions
- Medicines that themselves prolong the QT interval
This issue is especially relevant when considering a vardenafil product that is already far above the standard 20mg dose range.
Vardenafil and Heart Rhythm Medicines
Vardenafil should generally be avoided with certain antiarrhythmic medicines that can prolong the QT interval.
Examples listed in licensed prescribing information include:
- Quinidine
- Procainamide
- Amiodarone
- Sotalol
Anyone with a diagnosed heart-rhythm disorder should make sure that the prescriber knows their complete medication history before vardenafil is considered.
How Long Before Sex Is Vardenafil Normally Taken?
Licensed vardenafil film-coated tablets are generally taken approximately 25 to 60 minutes before anticipated sexual activity.
Vardenafil is absorbed relatively quickly.
In pharmacokinetic studies, peak blood concentrations occurred in some men as early as 15 minutes, although in around 90% of cases peak concentrations were reached within approximately 30 to 120 minutes.
Clinical erectile responses have been observed relatively early after dosing, but that should not be turned into a guarantee that every tablet works within exactly 15 minutes.
Individual response varies.
How Long Does Vardenafil Last?
Vardenafil is shorter acting than tadalafil.
Its terminal half-life is approximately four to five hours.
That does not mean an erection lasts four or five hours.
Instead, vardenafil creates a period during which the natural erectile response to sexual stimulation may work more effectively.
The exact useful treatment window varies between individuals.
Does Vilitra 60mg Last Three Times Longer Than 20mg?
No.
Tripling the tadalafil… wait, wrong PDE5 inhibitor. And that little slip actually illustrates the problem with thinking only in milligrams.
Vardenafil 60mg contains three times as much vardenafil as a 20mg tablet, but that does not mean the medicine lasts three times longer.
Drug duration depends on pharmacokinetics, metabolism and receptor effects rather than simple multiplication.
The more predictable consequence of higher exposure is greater potential for unwanted effects.
Does Vilitra 60mg Cause an Automatic Erection?
No.
Vardenafil requires sexual stimulation to produce its beneficial erectile effect.
The medicine enhances the natural nitric oxide and cGMP pathway after sexual arousal occurs.
It does not function as an automatic erection switch and does not directly increase libido.
Can You Take Vilitra 60mg Every Day?
60mg is not a standard daily vardenafil dose.
For licensed vardenafil treatment, the maximum recommended dosing frequency is once per day, but that statement applies within the established dose range of up to 20mg.
It should not be interpreted as approval to take 60mg every day.
A high-strength product should not be converted into a routine daily regimen without appropriate medical evidence and supervision.
Can You Take Three Vardenafil 20mg Tablets?
Three 20mg tablets would provide 60mg vardenafil.
That is three times the maximum recommended standard ED dose.
If 20mg does not work as expected, independently stacking additional tablets is not the established treatment pathway.
A healthcare professional should review why standard vardenafil has failed and whether another treatment would be more suitable.
What Happens If You Take Too Much Vardenafil?
Higher vardenafil exposure does not guarantee better erections.
Controlled studies have administered high vardenafil doses, but increased exposure can produce more adverse effects.
Notably, when 40mg vardenafil was given twice daily in overdose studies, cases of severe back pain were reported.
If significantly more vardenafil than intended has been taken, medical advice should be sought, particularly if symptoms occur.
What Are the Side Effects of Vardenafil?
The most commonly reported vardenafil side effect is headache.
Other common effects include:
- Dizziness
- Facial flushing
- Nasal congestion
- Indigestion
Less common effects can include:
- Nausea
- Reflux
- Abdominal discomfort
- Visual disturbance
- Changes in colour perception
- Light sensitivity
- Palpitations
- Fast heart rate
- Back pain
- Muscle aches
When to Seek Urgent Medical Attention
Seek urgent medical help for symptoms including:
- Chest pain
- Severe faintness or fainting
- A severe allergic reaction
- A seizure
- Sudden serious vision problems
- Sudden significant hearing loss
- A painful erection lasting four hours or longer
- Serious heart-rhythm symptoms
A prolonged painful erection is a medical emergency and requires urgent treatment.
Can Vardenafil Lower Blood Pressure?
Yes. Vardenafil has vasodilating properties and can cause a mild, temporary reduction in blood pressure.
For many suitable men using standard doses, this is not clinically significant.
The effect becomes considerably more important when vardenafil is combined with medicines that also influence blood pressure.
The most important example is nitrate medication.
Vardenafil and Nitrates
Vardenafil must not be combined with nitrate medicines or nitric oxide donors.
Nitrates are commonly prescribed for angina and certain other cardiovascular conditions.
Combining them with vardenafil can cause a dangerous fall in blood pressure.
This includes recreational nitrites commonly known as “poppers.”
Nicorandil also deserves attention because it has a nitrate component and can therefore interact seriously with vardenafil.
Vardenafil and Riociguat
Vardenafil should not be combined with riociguat.
Riociguat stimulates soluble guanylate cyclase and is used for certain forms of pulmonary hypertension.
Combining it with a PDE5 inhibitor can produce additive blood-pressure lowering.
Licensed vardenafil guidance therefore lists this combination as contraindicated.
Vardenafil and Alpha-Blockers
Alpha-blockers are used for conditions such as high blood pressure and urinary symptoms associated with an enlarged prostate.
Examples include:
- Tamsulosin
- Terazosin
- Alfuzosin
- Doxazosin
Both alpha-blockers and vardenafil can lower blood pressure.
Clinical interaction studies have reported hypotension, sometimes with symptoms, when vardenafil was combined with certain alpha-blockers.
Anyone using an alpha-blocker should mention it during assessment before taking vardenafil.
Vardenafil and CYP3A4 Drug Interactions
Vardenafil is metabolised primarily by the CYP3A4 enzyme system.
This creates some particularly important drug interactions because CYP3A4 inhibitors can dramatically increase the amount of vardenafil in the bloodstream.
Examples include:
- Ketoconazole
- Itraconazole
- Ritonavir
- Indinavir
- Erythromycin
- Clarithromycin
The scale of some interactions can be substantial.
For example, ritonavir has been shown to increase vardenafil exposure many times over and dramatically extend its half-life.
This is one reason unusually high-strength vardenafil becomes especially concerning when interacting medicines are involved.
Vardenafil and Grapefruit
Grapefruit and grapefruit juice can interfere with intestinal CYP3A4 metabolism and increase vardenafil concentrations.
Licensed prescribing information recommends avoiding the combination.
With standard-dose vardenafil this interaction already matters. With a product containing substantially more vardenafil than the licensed maximum, adding anything that further increases exposure is particularly undesirable.
Does Food Affect Vardenafil?
Vardenafil can be taken with or without food.
However, a high-fat meal can delay the onset of film-coated vardenafil tablets.
Studies found that a meal containing a high proportion of fat delayed the time to maximum concentration and reduced the peak concentration.
A more moderate-fat meal did not produce the same clinically relevant change.
If someone wants the most predictable onset, a very heavy meal immediately beforehand may therefore be less than ideal.
Can You Drink Alcohol With Vardenafil?
Controlled studies using standard vardenafil doses did not show a significant pharmacokinetic interaction with a moderate experimental alcohol exposure.
That does not make heavy drinking a good partner for ED treatment.
Too much alcohol can make it harder to achieve an erection in its own right and can contribute to dizziness or impaired judgement.
Moderation makes more sense when assessing whether an ED medicine is working properly.
Who Should Not Take Vardenafil?
Vardenafil is not suitable for everyone.
It is contraindicated with nitrates and riociguat and may be unsuitable in people with significant cardiovascular disease.
Licensed prescribing information also lists important restrictions involving people with:
- Very low blood pressure
- A recent heart attack
- A recent stroke
- Unstable angina
- Severe heart failure
- End-stage kidney disease requiring dialysis
- Severe liver impairment
- Certain hereditary retinal disorders
- Previous NAION-related vision loss
- Relevant QT-prolongation risk factors
Cardiovascular fitness for sexual activity should also be considered before ED medication is prescribed.
Does Vardenafil Increase Testosterone or Sex Drive?
No. Vardenafil is not testosterone replacement therapy and does not directly increase libido.
Its established effect is on the physical blood-flow mechanism involved in erections.
If the main problem is persistently low sexual desire rather than difficulty obtaining an erection, increasing vardenafil is unlikely to address the underlying issue.
Vilitra 60mg vs Sildenafil
Vardenafil and sildenafil are closely related PDE5 inhibitors.
| Feature | Vardenafil | Sildenafil |
|---|---|---|
| Medicine class | PDE5 inhibitor | PDE5 inhibitor |
| Typical starting dose | 10mg | 50mg |
| Maximum standard dose | 20mg | 100mg |
| Sexual stimulation required | Yes | Yes |
| High-fat food can delay onset | Yes | Yes |
The different milligram numbers cannot be compared directly.
Twenty milligrams of vardenafil is not “one fifth as strong” as sildenafil 100mg. They are different molecules with different therapeutic dose ranges.
Vilitra 60mg vs Tadalafil
Vardenafil and tadalafil both inhibit PDE5 but have noticeably different durations.
Vardenafil has a terminal half-life of roughly four to five hours.
Tadalafil has a much longer half-life of around 17.5 hours and can support erectile responsiveness for up to 36 hours.
Tadalafil may therefore suit someone who values a wider treatment window, while vardenafil provides a shorter on-demand approach.
Neither is universally better. Individual response, side effects and health conditions matter.
What If Vardenafil 20mg Does Not Work?
If an appropriate 20mg vardenafil dose has repeatedly failed, taking progressively larger tablets is not the standard next step.
A healthcare professional may consider:
- Whether the medicine has been taken correctly
- Whether a high-fat meal delayed its action
- Whether adequate sexual stimulation was present
- Cardiovascular health
- Diabetes
- Hormone levels
- Psychological factors
- Other medicines that may contribute to ED
- A different PDE5 inhibitor
- Non-tablet ED treatment
Treatment failure is a reason to reassess the treatment, not necessarily a reason to triple it.
Is Vilitra 60mg Available in the UK?
Vilitra 60mg is manufactured for international markets and can be found through overseas medicine suppliers.
Vardenafil itself is an established prescription medicine used for erectile dysfunction in the UK.
However, licensed UK vardenafil products use substantially lower strengths, with 20mg as the maximum recommended standard dose.
I could not verify Vilitra 60mg as an MHRA-authorised UK medicine.
The fact that an overseas website will ship a medicine to a UK address does not establish UK marketing authorisation for that product.
Buying Vardenafil Online in the UK
Online erectile dysfunction treatment can be private and convenient when there is a legitimate healthcare service behind the website.
A responsible provider should ask about:
- Your erectile dysfunction symptoms
- Cardiovascular health
- Blood pressure
- Nitrate medicines
- Heart-rhythm problems
- Other prescription medicines
- Kidney and liver health
- Previous response to ED treatment
Those questions become particularly important when a product contains three times the normal maximum vardenafil dose.
A supplier willing to provide high-dose ED medication without meaningful medical screening should be treated cautiously.
Frequently Asked Questions About Vilitra 60mg
What is Vilitra 60mg?
Vilitra 60mg is a tablet marketed as containing 60mg of vardenafil, a PDE5 inhibitor used for erectile dysfunction.
What is Vilitra 60 used for?
Vilitra is marketed for erectile dysfunction. Vardenafil improves the natural erectile response to sexual stimulation by supporting increased blood flow to the penis.
Is vardenafil 60mg a normal dose?
No. Licensed vardenafil treatment normally begins at 10mg and may be increased to a maximum of 20mg. Sixty milligrams is three times the maximum recommended standard ED dose.
Is Vilitra 60mg stronger than Vilitra 20mg?
Vilitra 60mg contains three times the stated vardenafil amount of a 20mg tablet, but that does not mean it provides three times the erectile benefit or duration.
Does vardenafil 60mg work better than 20mg?
60mg is not the standard recommended next step when 20mg fails. A poor response to maximum-dose standard vardenafil should be medically reviewed rather than the dose being independently tripled.
Have high doses of vardenafil been studied?
Yes. Single doses up to 80mg have been studied in controlled volunteer research, but this does not make those doses standard erectile dysfunction treatments.
How long before sex is vardenafil normally taken?
Licensed film-coated vardenafil tablets are generally taken approximately 25 to 60 minutes before anticipated sexual activity.
How long does vardenafil last?
Vardenafil has a terminal half-life of approximately four to five hours. Its practical erectile treatment window varies between individuals.
Does Vilitra 60mg cause an automatic erection?
No. Vardenafil requires sexual stimulation to produce its erectile effect and does not directly increase sexual desire.
Can you take Vilitra 60mg every day?
60mg is not a standard daily vardenafil dose. Licensed vardenafil treatment uses doses up to 20mg with a maximum recommended frequency of once per day.
Can I take three vardenafil 20mg tablets?
Three 20mg tablets would equal 60mg vardenafil, which is three times the maximum recommended standard ED dose. Do not independently increase the dose this way.
Does food affect vardenafil?
Vardenafil can be taken with or without food, but a high-fat meal can delay the onset of film-coated tablets.
Can you drink alcohol with vardenafil?
Controlled studies did not show a major interaction with moderate experimental alcohol exposure, but heavy alcohol consumption can worsen erectile function and contribute to dizziness.
Can vardenafil be taken with nitrates?
No. Vardenafil must not be combined with nitrate medicines or nitric oxide donors because the combination can cause a dangerous fall in blood pressure.
Can vardenafil be taken with riociguat?
No. Vardenafil and riociguat are contraindicated together because the combination can produce excessive blood-pressure lowering.
Does grapefruit interact with vardenafil?
Yes. Grapefruit can increase vardenafil concentrations by interfering with CYP3A4 metabolism, so the combination should be avoided.
Can vardenafil affect heart rhythm?
Vardenafil can prolong the QT interval. Particular caution is required in people with QT-related risk factors or medicines that also prolong the QT interval.
What are the common side effects of vardenafil?
Headache is the most common side effect. Dizziness, flushing, nasal congestion and indigestion are also commonly reported.
What should I do if vardenafil 20mg does not work?
Seek medical advice rather than automatically increasing the dose. Timing, food, cardiovascular disease, diabetes, hormones, psychological factors and other medicines can all influence treatment response.
Can you buy Vilitra 60mg in the UK?
Vilitra 60mg may be offered by international suppliers, but 60mg is not a standard licensed UK vardenafil dose. UK patients should use an appropriately regulated healthcare service or registered pharmacy when seeking ED treatment.
Important Medical Information
This page provides general information about Vilitra 60mg, vardenafil and erectile dysfunction. It is not personalised medical advice and should not replace assessment by a doctor, pharmacist or appropriately qualified prescriber.
Vilitra 60mg is marketed as containing 60mg vardenafil. Licensed UK vardenafil treatment normally starts at 10mg and has a maximum recommended dose of 20mg.
Vardenafil must not be combined with nitrates or riociguat. Important interactions also exist with several CYP3A4 inhibitors, alpha-blockers, grapefruit and medicines that can prolong the QT interval.
Seek urgent medical attention for chest pain, fainting, serious heart-rhythm symptoms, a severe allergic reaction, sudden significant vision or hearing problems, a seizure or a painful erection lasting four hours or longer.


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